GenSolve™: The GenSolve kit recovers double stranded DNA from paper spotted with blood or other biological liquids, regardless of storage time, for subsequent purification. DNA can be efficiently recovered at higher yield from treated paper, i.e. FTA, and untreated paper, i.e. Guthrie cards than using other techniques.
The GenSolve reagents coupled with recovery process enhances digestion of dried biological material and liberates more bound DNA from the paper. The resulting lysate, which is a mixture of DNA, cellular debris and FTA chemicals, if applicable, is then applied directly onto a purification membrane. Subsequent washing steps separate the DNA from cellular material and a final elution step results in purified DNA ready for most genetic analysis techniques or for long term storage using GenTegra-DNA.